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Resilient Option - finding strength and connection

PlanScape Impact(s): Aging ; Best Practice ; Chronic Illness ; Diversity and Inclusion ; Health ; Mental Health
Last modified: April 02, 2020 Public Report From Resilient Living (A Happy Brain)


Dr. Amit Sood



Someone ungrateful in your life? 


Dear friend,
You went above and beyond to help someone. But that person never said thank you. Later, when you were in the same elevator with that person, he or she avoided greeting you. Sounds familiar? 
Earlier, I used to get upset with such people or felt something was wrong with me. Now, genetic research is helping me think differently. 
We all have a gene called CD38 that mediates the secretion of oxytocin.(1) Oxytocin is the hormone of bonding and affiliation.(2) People with high oxytocin are good at feeling and expressing gratitude. People with low oxytocin aren’t as good.
The CD38 gene comes in several variations. Some variations lead to higher oxytocin in the body; other variations lead to lower oxytocin. Interestingly, ungrateful people have low CD38 expression. 
So, instead of calling someone ungrateful, I now call him or her the low CD38 person!
If you struggle with an ungrateful person, then decrease the dose of that person in your life (as much as you can).  Invest more time with people who have high CD38 – the grateful and the kind ones. 
If you can’t remove the low CD38 people from your life, then see them as a four-year-old in a forty-year-old body. Do not let them usurp the precious real estate in your brain. That’s being kind to yourself. 

Take care.

1: Algoe SB, Way BM. Evidence for a role of the oxytocin system, indexed by genetic variation in CD38, in the social bonding effects of expressed gratitude. Soc Cogn Affect Neurosci. 2014 Dec;9(12):1855-61. doi: 10.1093/scan/nst182. Epub 2014 Jan 5. PubMed PMID: 24396004; PubMed Central PMCID: PMC4249462.
2: Feldman R. Oxytocin and social affiliation in humans. Horm Behav. 2012 Mar;61(3):380-91. doi: 10.1016/j.yhbeh.2012.01.008. Epub 2012 Jan 20. Review. PubMed PMID: 22285934.

Amit Sood, MD MSc




PlanScape Impact(s): Aging ; Best Practice ; Chronic Illness ; Diversity and Inclusion ; Health ; Mental Health
Last modified: April 02, 2020 Public Report From Resilient Living (A Happy Brain)

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  • For the commercial sector, we tend to register startup activities (new companies and new commercial projects) that bring diversification and high-impact opportunities to the area.
  • For the non-profit sector, we wish to shine light on all the organizations and services that otherwise labor under relative obscurity.
  • Our hope is that will encourage cross-sector collaborations and creative solutions.

While there are a number of registries in the community,'s  distinct value is to pilot a database with a data structure and categorizations that answer the questions such as: What organizations or projects/programs in our community that have purported relevance with some of the over-arching focuses put forward by initiatives such as DMC, J2G and Health Improvements?

This database could be used as one of the ways to explore the capacities of the community. If you are someone on an exploratory journey to learn about the greater Rochester community. could be an interesting first step.

The following defines the various project phases:
  1. Available - a product, program or service is in production
  2. Develop - program or application is being developed
  3. Plan - idea is solid, stakeholders are identified, and there is strong commitment to go forward from all parties.
  4. Concept Phase - idea scoped out with enough details to give an early sizing and/or to build a proof of concept
  5. Pre-concept Phase - an early idea or a requirement.
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